What's the most complicated part of being a physician's assistant?

The physician assistant profession (not physician's assistant fyi) is very flexible. The hardest part is finding the specialty, doctor, and clinic that fits you the best. Shadow people in specialties you think you're interested in, ask them about their work/home balance, about the annoying parts of their jobs, and remember that half your time in PA school is doing rotations. This means you live the life of a provider family practice, emergency medicine, surgery, etc. for 4-6 weeks. You learn a lot about the job and the annoying/complicated things associated with it and also about the life your preceptor leads. The best way to learn what's complicated/good/bad about a job is to try it.

TL;DR The most complicated part of being a PA depends on what type of PA you are.

I'd say the most complicated part about being a PA is getting through the rigorous school. The average PA program is 24-27 months in length. Most programs are divided into a didactic (classroom) year and clinical year. The first year (didactic) is very rigorous with a lot of information to be learned. Be prepared to devoted two years of your life to school. This is not to scare you, but it is simply prepare you to make the necessary personal/professional adjustment. Additionally, due to it's demand it'd be highly advised that you do not work during that time. The second year is more practical as you can apply your knowledge to hands on stuff. it's really fun. Becoming a PA demanda a lot from you especially the first year of school, but with sacrifices, commitment and dedication it is certainly possible. fyi- it's Physician (NOT physician's) Assistant. :) hope this helps