What is the best course will i choose after class 10

It totally based in what subject you are good at ? Eg. If you are good at Physics & Mathematics you can opt for Engineering or Medical, In case if you are an average student you would like to go for Commerce field.

1) What do you want to be?
Which field do you want to work in? Do some research about the required qualifications for that line.

2) Determine what are your likes.

What do YOU like?

Do you like physics? If yes, you can think of going into science.

Do you like chemistry? If yes, science is a good option.

Do you like biology? Medical is a good option.

Do you like maths? Commerce or non-medical could be your thing.

Do you like English and are you good at it? If yes, Humanities could be your thing.

3) Assess your marks in each subject.
You need to score well in twelfth and thereafter to get into a good college and be successful. So do consider taking the line where you score well.

4) Talk to your teachers and parents.
Don't let anyone pressurize you into pursuing a field you don't like. But do ask for their opinion because they are your well wishers.

In the end, don't take a certain stream just because everyone is taking it or because your friends are taking it. Do what YOU want. And don't be hasty in your decision.

I completely agree with Samir and also Whatever field you choose always ensure you master the skills that will definitely give you good career.